Glycine Health Benefits

The anti-ageing health benefits of Glycine have recently been published in an important, peer reviewed scientific paper, entitled: Glycine & Ageing: Evidence & Mechanisms¹. This paper, published in March 2023, supports what has been understood by the natural health community for many years, that being, Glycine supports detoxification and likely extends life.

But, extending life on its own, is not always a good thing. Quality of life is of utmost importance.

Extended lifespan, when there is a poor quality of life, would be seen undesirable by many.

The fact that Glycine extends life, whilst also supporting quality of life, is immensely important.

Another Study Focusses On The Following

Glycine has a protective effect in lung, brain, stomach, and intestine; participates in metabolic process; modulate process of the immune system such as tissue regeneration, decrease necrosis, sepsis protection; and finally, glycine is considerate as a genic expression modulator. Glycine plays a role in diabetes… There have been many studies focused on the anti-inflammatory effects of glycine, including its abilities to decrease pro-inflammatory cytokines and the concentration of free fatty acids, to improve the insulin response, and to mediate other changes… Although glycine is a non-essential amino acid, we highlight how dietary glycine supplementation is important in avoiding the development of chronic inflammation.²

Glycine Skin Health Benefits

Glycine is essential for producing collagen, the connective tissue that gives our skin its integrity.

Insufficient glycine in our diet will lead to signs of ageing becoming more evident. This is because glycine reduces our predisposition to show signs of ageing, such as developing wrinkles and losing the plump, youthful appearance of our skin.

Life Extending Benefits of Glycine

Glycine increases autophagy and restricts methionine. Both of these actions increase life-expectancy.

Autophagy allows our bodies to break down and reuse old cell parts so that our cells can function more efficiently.

Methionine is a unique sulphur-containing amino acid. Whilst necessary for the body, excess methionine can disrupt detoxification processes, known as methylation. So, the fact that glycine can regulate excess methionine is important. The new study, mentioned above, shows that methionine restriction is an important factor in increasing lifespan.

Additional Benefits Of Glycine

The study also highlighted how glycine helps reduce the incidence and severity of age related diseases.

Some of the best outcomes of the study are as follows:

• Reduces risk of obesity
• Reduces risk of strokes
• Improves bladder function
• Reduces risk of diabetes
• Reduces risk of cancer
• Reduces risk of metabolic disorder
• Reduces fatigue levels
• Improves brain function
• Improves sleep quality & reduces insomnia

Glycine & NAC

Both glycine and N-Acetylcysteine (NAC) are precursors to glutathione production within the body.

Glutathione, is the major antioxidant made and used by our body to eliminate toxicity.

In a randomised clinical trial, the results of supplementing with glycine in conjunction with N-Acetylcysteine were exceptional.

The name of the study says it all…

Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks

Sources:

1. https://pubmed.ncbi.nlm.nih.gov/37004845/
2. https://pmc.ncbi.nlm.nih.gov/articles/PMC10379184/